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Study of anticlastogenic effect of spirulina against arsenic using zebra fish by micronucleus method


Sayantani Chanda1 *, T. V. Ramachandra2, Puspal Dey3 , Madhumita Joarder Mukhopadhay4

1,2, Energy & Wetlands Research Group, Centre for Ecological Sciences [CES],
Indian Institute of Science, Bangalore, Karnataka, 560 012, India,
Web URL: http://ces.iisc.ernet.in/energy; http://ces.iisc.ernet.in/foss,
3,4, Maulana Abul Kalam Azad University of Technology, Kolkata, (W.B.) - India
*Corresponding author:E.mail: isayantani.chanda@gmail.com


Abstract

Arsenic is a potent toxic chemical that causes ground water contaminant. Nowadays different health hazards causes due to Arsenic toxicity when common people exposed to contaminated water. To reduce harmful toxic effect of Arsenic it is a big challenge for researcher to find out the easy and cheaper way. The study aims to explore the potential of using Spirulina which can ameliorate the toxic effect of Arsenic by its antagonistic properties in zebra fish. We use zebra fish as a model organism which uses as indicator for aquatic pollution study. This experiment 10 ml stock solution sodium arsenite (30mg dissolved in 100ml) is used. The present study shows that Spirulina a known antioxidant food, already used by human being is able to decrease is able to decrease moderately theincidence of micronucleus formation.

Keywords: Arsenic, Spirulina, Micronucleus